Inactives:
- QB Brandon Allen
- DL Alex Barrett
- WR Ronnie Bell
- LB Jalen Graham
- DL T.Y. McGill
- OL Matt Pryor
- CB Samuel Womack
Defensive tackle Kalia Davis (ankle) was initially declared "questionable" for the game but was downgraded to "out" on Saturday. He was never activated from the injured reserve list.
On Saturday, the 49ers elevated defensive linemen Alex Barrett and T.Y. McGill from the practice squad. However, neither is active.
The following six Chiefs players are inactive:
- CB Ekow Boye-Doe
- LB Darius Harris
- RB La'Mical Perine
- WR Justyn Ross
- DE BJ Thompson
- WR Kadarius Toney
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