As expected, Arik Armstead has been ruled out of this weekend's game, having missed practice throughout the week due to knee and foot injuries. Head coach Kyle Shanahan anticipated the unavailability of his defensive lineman against the Seahawks.
Tight end Ross Dwelley has also been ruled out, having suffered a high-ankle sprain that will sideline him for multiple games.
Also missing Friday's practice were guard Spencer Burford, cornerback Darrell Luter, wide receiver Ray-Ray McCloud, and running back Elijah Mitchell. All except McCloud, who was limited on Wednesday, missed the entire week of practice. McCloud has been ruled out, while the other three are listed as "doubtful."
With Mitchell listed as "doubtful," Shanahan noted that the 49ers would "most likely" elevate a running back from the practice squad for Sunday's game. The candidates are Tyrion Davis-Price and Jeremy McNichols.
On the Seahawks' side, quarterback Geno Smith is among several players listed as "questionable."
Below are the official injury reports for the 49ers and Seahawks, provided by the 49ers Communications staff. Also included are Friday's practice participation reports.
San Francisco 49ers
Out
DT Arik Armstead (foot, knee), TE Ross Dwelley (ankle), WR Ray-Ray McCloud (rib)
Doubtful
G Spencer Burford (knee), CB Darrell Luter (hamstring), RB Elijah Mitchell (knee)
Seattle Seahawks
Questionable
LB Jordyn Brooks (ankle), CB Tre Brown (heel), RB Zach Charbonnet (knee), WR D'Wayne Eskridge (ribs), DT Jarran Reed (hamstring), QB Geno Smith (groin), RB Kenneth Walker (oblique)
San Francisco 49ers Friday Practice
Did Not Participate In Practice
DT Arik Armstead (foot, knee), G Spencer Burford (knee), TE Ross Dwelley (ankle), CB Darrell Luter (hamstring), WR Ray-Ray McCloud (rib), RB Elijah Mitchell (knee)
Seattle Seahawks Friday Practice
Did Not Participate In Practice
DT Jarran Reed (hamstring), QB Geno Smith (groin)
Limited Participation in Practice
LB Jordyn Brooks (ankle), CB Tre Brown (heel), WR D'Wayne Eskridge (ribs)
Full Participation in Practice
S Jamal Adams (knee), WR Jake Bobo (knee, shoulder), G Anthony Bradford (knee), C Evan Brown (thumb), RB Zach Charbonnet (knee), T Abraham Lucas (knee), RB Kenneth Walker (oblique), DT Leonard Williams (ankle), WR Dareke Young (abdomen)
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