San Francisco is without one of its starting safeties. Talanoa Hufanga suffered a torn ACL against the Tampa Bay Buccaneers and will miss the remainder of the season. Rookie Ji'Ayir Brown will start in his place.
The 49ers took the field without starting guard Spencer Burford, who is dealing with a knee injury. He was among the team's seven inactive players for the matchup.
Below are the 49ers-related in-game injury updates.
S George Odum (biceps, out)
George Odum was injured in the second quarter during a special teams play that saw Seahawks running back DeeJay Dallas mishandle a kick-off catch, leading to a scramble by several players for possession of the football. 49ers wide receiver Ronnie Bell ended up with the football.
The 49ers ruled Odum out for the remainder of the game due to a biceps injury. That leaves the team with little depth at safety.
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