McCaffrey suffered an oblique/rib injury in the third quarter of Sunday's loss, while Samuel sustained a shoulder injury in the first quarter. Williams injured his ankle in the first quarter but was able to play through the pain.
Schefter reports that none of these injuries appear to be long-term, including McCaffrey's, giving hope that all three may be available for the Week 7 clash against the Minnesota Vikings.
The 49ers will hold their first practice of the week on Thursday, followed by Friday and Saturday sessions. They will then travel to Minneapolis before Monday's game at U.S. Bank Stadium.
Related News
More San Francisco 49ers News
-
Christian McCaffrey reacts to 49ers wanting to reduce his workload
San Francisco 49ers running back Christian McCaffrey logged 932 offensive snaps last season, accounting for 83 percent of the team's offensive plays—his highest snap count since 2019. His 413 touches led the NFL. McCaffrey made the most of those opportunities, totaling 2,126... -
49ers hope to adjust Christian McCaffrey plan in 2026
After an injury-plagued 2025 season, Christian McCaffrey responded with a remarkable bounce-back 2026 campaign for the San Francisco 49ers, totaling 2,126 scrimmage yards and 17 touchdowns on a league-high 413 touches en route to NFL Comeback Player of the Year honors. It was... -
49ers mailbag: How much will Kaelon Black play as a rookie? Will SF sign any more free agents? Will the defense be any better in 2026?
The San Francisco 49ers have started OTAs (organized team activities), and there's finally actual football to discuss. It may not be like training camp, but it's close enough. And training camp isn't too far away. We opened the 49ers Webzone Mailbag to see what was on your... -
49ers QB Brock Purdy proved unlucky in one category by PFF
San Francisco 49ers quarterback Brock Purdy threw 13 interceptions during his injury-shortened 2025 season, including the playoffs. According to analytics site Pro Football Focus (PFF), only 12 of his passes were deemed turnover-worthy, yet nine of those throws resulted in...