Johnson went down on special teams late in the second quarter. He managed to walk to the locker room under his own power. The 49ers later ruled him out due to the knee injury.
Sunday was Johnson's second game appearance this season. He played nine snaps on special teams against the Buccaneers. Johnson, a locker-room favorite, was also active for Week 6 against the Atlanta Falcons when he played 18 snaps on defense and seven on special teams.