The San Francisco 49ers are playing the Seattle Seahawks at Levi's Stadium. It is the Niners' home opener. The team entered the matchup without tight end George Kittle and offensive lineman Daniel Brunskill. The former is dealing with a groin strain, while the latter is attempting to return from a hamstring injury. Both are among five inactive players for the 49ers.

Below are the 49ers-Seahawks in-game injury updates.


QB Trey Lance (ankle, ruled out)


Jimmy Garoppolo entered the game for injured quarterback Trey Lance, who went down late in the first quarter. Lance was carted off the field after sustaining what appeared to be a lower right leg injury. The leg was placed in an air cast as he headed to the locker room.

Update: Lance has been ruled out with a right ankle injury.


TE Tyler Kroft (knee, out)


The 49ers ruled out Tyler Kroft with a knee injury. San Francisco entered the game without All-Pro tight end George Kittle (inactive, groin strain). Tight end Ross Dwelley hauled in a 38-yard touchdown pass from Garoppolo in the second quarter.

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