49ers-Seahawks Injury Updates: Trey Lance carted off the field, replaced by Jimmy Garoppolo

The San Francisco 49ers are playing the Seattle Seahawks at Levi's Stadium. It is the Niners' home opener. The team entered the matchup without tight end George Kittle and offensive lineman Daniel Brunskill. The former is dealing with a groin strain, while the latter is attempting to return from a hamstring injury. Both are among five inactive players for the 49ers.

Below are the 49ers-Seahawks in-game injury updates.

QB Trey Lance (ankle, ruled out)

Jimmy Garoppolo entered the game for injured quarterback Trey Lance, who went down late in the first quarter. Lance was carted off the field after sustaining what appeared to be a lower right leg injury. The leg was placed in an air cast as he headed to the locker room.

Update: Lance has been ruled out with a right ankle injury.

TE Tyler Kroft (knee, out)

The 49ers ruled out Tyler Kroft with a knee injury. San Francisco entered the game without All-Pro tight end George Kittle (inactive, groin strain). Tight end Ross Dwelley hauled in a 38-yard touchdown pass from Garoppolo in the second quarter.

Related News

• Trey Lance carted off in first quarter
  Pro Football Talk
• Trey Lance carted off after big hit, ruled out with ankle injury
  Niners Wire
• 49ers QB Trey Lance Announced Out with Ankle Injury
  49ers.com
• 49ers' Trey Lance suffers broken ankle vs. Seahawks, will miss rest of season
  The Mercury News
• 49ers QB Trey Lance knocked out of game with broken ankle
  San Francisco Chronicle
• Jimmy Garoppolo throws TD pass after replacing injured Trey Lance
  Touchdown Wire
• 49ers QB Trey Lance carted off field with right ankle injury
  Touchdown Wire
• Trey Lance injury: 49ers keeping Jimmy Garoppolo looks like smart move
  NBCS Bay Area
• 49ers rule out TE Tyler Kroft with knee injury
  Niners Wire

More San Francisco 49ers News

• 49ers rookie Romello Height avoids serious injury after being carted off the practice field

  San Francisco 49ers rookie defensive end Romello Height suffered an injury during Monday's practice, the second session of training camp. The third-round pick was carted off the field following a concerning moment. Scary moment at practice and rookie 49ers DL Romello Height is...
  Read Article

• 49ers training camp: Shanahan observes, Warner returns, Evans impresses, injury updates

  The San Francisco 49ers officially reported to training camp this weekend, holding their first practice on Sunday. The session was open to fans, offering an early glimpse at how the team is taking shape ahead of the upcoming 2026 campaign. Before practice, the 49ers announced...
  Read Article

• How will Kyle Shanahan's absence affect the 49ers on the field?

  Kyle Shanahan's absence will undoubtedly be felt by the San Francisco 49ers. The question is how much it will affect them on the field. His absence will obviously be felt much more if he were to miss games, but how about training camp? According to ESPN's Adam Schefter,...
  Read Article

• 49ers coach Chris Foerster shares training camp updates

  San Francisco 49ers assistant head coach and offensive line coach Chris Foerster, who is serving as the team's interim head coach, spoke with reporters on Sunday following the first training camp practice. Here's everything he had to say. Transcript provided by the San...
  Read Article