Below are the 49ers-Colts in-game injury updates.
SS Jaquiski Tartt
Tartt suffered a knee injury. In the fourth quarter, the 49ers announced that the safety had been ruled out for the remainder of the game. Rookie Talanoa Hufanga replaced Tartt.
CB Emmanuel Moseley
Moseley remained down on the field after an impact with teammate Azeez Al-Shaair on a tackle of Colts receiver Michael Pittman. Dre Kirkpatrick replaced Moseley. After the game, head coach Kyle Shanahan said that Moseley suffered a back injury but returned to the game.
DE Dee Ford
After the game, Shanahan informed reporters that Ford was evaluated for a head injury.