The 49ers also announced the following roster moves:
- LT Trent Williams and LB Joe Walker have been activated from the reserve/COVID-19 list
- DL Alex Barrett has been activated from the practice squad (standard elevation)
- OL Tony Bergstrom, DL Darrion Daniels, and DL Willie Henry Jr. have been activated from the practice squad (COVID-19 replacement)
Sherman has been on injured reserve since September 16 due to a calf injury. He appeared in one game — a Week 1 loss to the Arizona Cardinals — this season.
Mostert landed on injured reserve with a high-ankle sprain on October 24. Wilson later suffered the same injury as Mostert and landed on IR a week after Mostert.
Running back JaMycal Hasty landed on injured reserve with a broken collarbone on November 17, and Tevin Coleman has been ruled out of Sunday's game due to a knee injury.
Mostert's 303 rushing yards still lead the team despite the running back having played in just four games this season.
The 49ers announced that both Williams and Walker are now listed as "questionable" to play on Sunday against the Los Angeles Rams. Their activation leaves the following four players still on the reserve/COVID-19 list, and unavailable for the game.
- WR Brandon Aiyuk
- TE Daniel Helm
- DT D.J. Jones
- DE Jordan Willis
Aiyuk and Helm have been on the reserve/COVID-19 list since November 20 while Jones and Willis have been since November 23.
Related News
More San Francisco 49ers News
-
49ers make several roster moves during OTAs, add two running backs
According to the NFL transaction wire, the San Francisco 49ers made several roster moves on Thursday as organized team activities (OTAs) continued. Signed RB Jordan Mims RB Jermar Jefferson Waived RB Sincere McCormick Placed on injured reserve DB Darrick Forrest The... -
Where does 49ers' Mac Jones rank among NFL backup QBs by trade value?
Mac Jones saved the San Francisco 49ers' season in 2025. That wasn't a statement any fan expected to hear before last season began. But it happened. And it's not an overreaction. Starting QB Brock Purdy missed eight games in 2025. And Jones filled in admirably, going 5-3, and... -
Two 49ers named among NFL's most underrated players
Pro Football and Sports Network's (PFSN) Jacob Infante highlighted 12 of the NFL's most underrated players from the 2025 season, and the list included two San Francisco 49ers contributors. Infante utilized PFSN's Impact Scoring metric, which assigns a numerical value to... -
49ers' roster overhaul reveals a fascinating trend under John Lynch
I have written in the past about what teams should consider when building a roster. Today, I will examine two trends that have emerged recently in 49erland. Trust the Conference In the past five seasons, the following receivers have been All-Pro selections. Ja'Marr...