Garoppolo went 11-of-16 for 84 yards and an interception before leaving with an ankle injury late in the third quarter.
It was some uninspiring play. Garoppolo's backup, Nick Mullens, entered the game in the fourth quarter and went 18-of-25 for 238 yards and threw two touchdown passes, making some wonder if the outcome of the 37-27 Seattle win would have been different had Mullens played the whole game.
Could Kyle Shanahan and the 49ers look to get out of Garoppolo's contract and part ways with their franchise quarterback after this season? ESPN believes so.
"San Francisco's injury situation this season is unrivaled league-wide, and it might be unfair to judge anyone as a result," wrote Dan Graziano. "But Garoppolo's inconsistencies -- be they of performance or availability -- have become too much for an otherwise steady team to ignore.
"Do they go with Mullens on Thursday against Green Bay, whether Garoppolo's ankle is fine or not? Do they think about making a switch in the second half of the season? It feels inevitable that they at least consider alternatives in the offseason, and the way Garoppolo's contract is structured allows them to replace him quite easily if that's what they decide to do."
The 49ers admittedly briefly flirted with the possibility of replacing Garoppolo with Tom Brady this past offseason. That was after the quarterback led the team to a Super Bowl appearance in his first full NFL season as a starter. The 49ers are now 4-4 and remain in last place within the NFC West, making one wonder what Shanahan and company might consider this offseason.
More San Francisco 49ers News
-
49ers injury news: Kyle Shanahan provides 3 key updates after win over Raiders
San Francisco 49ers head coach Kyle Shanahan spoke to reporters after Thursday night's 18-12 preseason win over the Las Vegas Raiders at Allegiant Stadium, providing three key injury updates from the game. Rookie cornerback Ephesians Prysock, a fourth-round pick in the 2026... -
49ers' Kyle Shanahan shifts focus to regular season: "It's going to get real, real fast"
The 2026 NFL preseason is in the books, and the San Francisco 49ers finished their exhibition schedule with an 18-12 win over the Las Vegas Raiders. Now, the focus shifts to the regular season, with San Francisco set to face the Los Angeles Rams in Melbourne, Australia, in Week... -
49ers projected 53-man roster: Final predictions before roster cuts
The San Francisco 49ers are just days away from trimming their roster to 53 players, and several positions remain difficult to project. Injuries, preseason performances, and the amount of playing time given to certain players have all provided clues about Kyle Shanahan and John... -
49ers Rookie Kaelon Black Has Chance to Seize RB2 Role Against Chargers
Many starters are in line to play tonight for the San Francisco 49ers as they take the field for their second preseason game, this time against the Los Angeles Chargers. Running back Christian McCaffrey and wide receiver Mike Evans are both dealing with tightness, while tight...