- Cornerback Parnell Motley has completed COVID-19 protocols, passed his physical, and is now on the team's active roster.
- Offensive lineman Ben Garland has been placed on injured reserve.
- Tight end Daniel Helm has been waived.
Garland suffered a calf strain on Sunday night against the Los Angeles Rams.
The following rundown was provided by the 49ers Communications staff.
Motley (6-0, 180) was claimed off waivers by the 49ers from the Tampa Bay Buccaneers on October 13, 2020. He will wear number 49.
Garland (6-5, 304) started in five of the team's six games this season, while Helm (6-4, 225) appeared in one game after signing with the team from the Tampa Bay Buccaneers practice squad on September 30, 2020.
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