All 10 participating staff members selected the 49ers to beat the Dolphins. San Francisco is currently an 8-point favorite.
As for all the fans who are taking part in our NFL Pick 'em contest, 95 percent have the 49ers winning the game, as of this post.
Of all the Week 5 game predictions, the most lopsided result comes from the matchup between the Cincinnati Bengals and the Baltimore Ravens on Sunday. Voting has 99 percent of fans believing the Ravens will earn the victory.
The closest matchup, when it comes to the predictions, is between the Indianapolis Colts and the Cleveland Browns on Sunday, with 51 percent selecting the Browns to win the game.
| Picks | Away | Home | Picks |
|---|---|---|---|
|
89%
|
Buccaneers
|
Bears
|
11%
|
|
17%
|
Jaguars
|
Texans
|
83%
|
|
1%
|
Bengals
|
Ravens
|
99%
|
|
96%
|
Rams
|
Washington
|
4%
|
|
2%
|
Eagles
|
Steelers
|
98%
|
|
98%
|
Cardinals
|
Jets
|
2%
|
|
2%
|
Raiders
|
Chiefs
|
98%
|
|
45%
|
Panthers
|
Falcons
|
55%
|
|
5%
|
Dolphins
|
49ers
|
95%
|
|
49%
|
Colts
|
Browns
|
51%
|
|
3%
|
Giants
|
Cowboys
|
97%
|
|
7%
|
Vikings
|
Seahawks
|
93%
|
|
6%
|
Broncos
|
Patriots
|
94%
|
|
8%
|
Chargers
|
Saints
|
92%
|
|
85%
|
Bills
|
Titans
|
15%
|
More San Francisco 49ers News
-
49ers standouts earn PFWA honors as Christian McCaffrey makes All-NFL Team
Running back Christian McCaffrey was the lone San Francisco 49ers player selected to the 2025 Professional Football Writers of America (PFWA) All-NFL Team. However, the 49ers were well represented on the All-NFC Team, with left tackle Trent Williams and linebacker Luke Gifford... -
49ers DC Robert Saleh to interview with Dolphins on Thursday
San Francisco 49ers defensive coordinator Robert Saleh said Wednesday that he didn't have any head coaching interviews scheduled until Sunday, following the team's Divisional Round playoff game against the Seattle Seahawks. That has changed. According to NFL Network insider... -
49ers QB Brock Purdy '100 percent' confident team can win Super Bowl next season
Despite his team looking like anything other than a Super Bowl contender in their 41-6 Divisional Round playoff loss to the Seattle Seahawks on Saturday night, San Francisco 49ers quarterback Brock Purdy seems extremely high on his team's chances as they head into 2026. Purdy... -
49ers' Kyle Shanahan sounds off on Ricky Pearsall injury concerns
There was significant excitement surrounding Ricky Pearsall's potential entering the season. The San Francisco 49ers wide receiver showed encouraging chemistry with quarterback Brock Purdy, leading many to believe Pearsall could emerge as a breakout performer in 2025. That...