Breida did not play last weekend against the Arizona Cardinals after aggravating an ankle injury during Week 10's matchup against the Seattle Seahawks.
"I think we've seen with Matt over the years, you look at players' history, and when he's been banged up, sometimes it's led to a situation where he can play, but he is continually having to come out with things," general manager John Lynch said this past week. "I think we're trying to just get him healthy because when he's healthy, he's a dynamic back. When compromised, he's a smaller guy, and it's tough for him to play effectively.
"So we want to get him fully healthy. I think that's been our focus and the word from the docs? A couple of weeks would help."
The good news is that three of quarterback Jimmy Garoppolo's most reliable targets, tight end George Kittle (knee, ankle) and wide receivers Deebo Samuel (shoulder) and Emmanuel Sanders (ribs), are all expected to play.
The only players ruled out of tonight's game are defensive end Dee Ford (quadricep, hamstring) and tackle Joe Staley (finger).
More San Francisco 49ers News
-
Shanahan shares tough injury news ahead of playoffs, Fred Warner update
The San Francisco 49ers are gearing up to face the Philadelphia Eagles at Lincoln Financial Field after dropping to the No. 6 seed in the NFC playoff standings following a Week 18 loss to the Seattle Seahawks. Head coach Kyle Shanahan spoke with reporters during a Monday... -
49ers roster news: Kendricks promoted to active roster; Bethune to IR; Cowing's practice window opened; Other moves announced
The San Francisco 49ers announced several roster moves on Wednesday. Linebacker Eric Kendricks has been promoted from the practice squad to the active roster. Linebacker Tatum Bethune has been placed on the injured reserve list. Linebacker Kyzir White has been signed to the... -
49ers vs. Eagles: Trent Williams and Ricky Pearsall won't practice Wednesday
San Francisco 49ers quarterback Brock Purdy sounded confident this week that left tackle Trent Williams would return for the team's Wild Card playoff game against the Philadelphia Eagles this weekend. However, head coach Kyle Shanahan expressed more caution, stopping short of... -
49ers vs. Eagles injury updates: George Kittle suffers Achilles injury
The San Francisco 49ers are facing the Philadelphia Eagles at Lincoln Financial Field in a Wild Card playoff game. Below are the latest in-game injury updates for the 49ers. This article will be updated in real time as new information becomes available. Players are listed in...