The 49ers beat the Cardinals 36-26 improving to 9-1 on the season.
Garoppolo finished the game with a 75.6 completion percentage, 424 passing yards, four touchdowns, two interceptions, and a passer rating of 115.4.
The other nominees for the FedEx Air Player of the Week are quarterbacks Dak Prescott of the Dallas Cowboys and Kirk Cousins of the Minnesota Vikings.
Samuel caught eight passes from Garoppolo for 134 receiving yards against the Cardinals.
The 49ers' rookie receiver is up against quarterback Kyler Murray of the Arizona Cardinals, running back Josh Jacobs and defensive end Maxx Crosby of the Oakland Raiders, and cornerback Marvell Tell of the Indianapolis Colts.
Fans can vote for Garoppolo below or by clicking here.
Fans can click here to vote for Samuel.
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