Head coach Kyle Shanahan revealed via a conference call on Tuesday that Staley suffered a fractured finger, which may require surgery. The offensive lineman is seeking a second opinion.
"He got out of the game fine with his leg," Shanahan said, "but he ended up having a finger fracture/dislocation. Right now, he's getting a second opinion on it, and we'll have more on that tomorrow, but surgery could be a possibility."
The good news is that Staley might only miss a couple of weeks due to the new injury. His replacement since Week 2, rookie Justin Skule, played well in the veteran's absence.