The names you'd expect to be at the top are there. Kansas City Chiefs quarterback Patrick Mahomes is the odds-on favorite, coming in at plus-400. Right behind him at plus-700 is New Orleans Saints quarterback Drew Brees, while quarterbacks Andrew Luck and Aaron Rodgers -- of the Indianapolis Colts and Green Bay Packers, respectively -- are tied for third on the list at plus-800.
The San Francisco 49ers have their own quarterback, Jimmy Garoppolo, on the list, too. His odds to secure the MVP award currently sit at plus-4000, which is tied for 14th along with Los Angeles Rams running back Todd Gurley, Pittsburgh Steelers quarterback Ben Roethlisberger, Carolina Panthers quarterback Cam Newton and Rams defensive tackle Aaron Donald.
At least Garoppolo is tied with the league's 2018 Defensive Player of the Year winner, Donald.
Garoppolo is coming off a 2018 campaign in which he suffered a torn ACL in Week 3. But the odds makers are certainly recalling the five-game win streak he helped engineer to close out the 2017 season after the 49ers acquired him via a trade with the New England Patriots earlier that year. Nearly two full years in head coach Kyle Shanahan's offense should help give Garoppolo a leg up on improving on what was a frustrating 2018 for the 27 year old. Additionally, San Francisco added a number of offensive weapons during the offseason to pair with Pro Bowl tight end George Kittle.
Perhaps this combination assists Jimmy G in bettering those odds as the season rolls along.
Garoppolo was the only 49ers player to wind up on MyBookie's list.
Written By:
Peter Panacy has been writing about the 49ers since 2011 for outlets like Bleacher Report, Niner Noise, 49ers Webzone, and is occasionally heard as a guest on San Francisco's 95.7 FM The Game and the Niners' flagship station, KNBR 680. Feel free to follow him, or direct any inquiries to his Twitter account.
All articles by Peter Panacy
Peter Panacy
Peter Panacy has been writing about the 49ers since 2011 for outlets like Bleacher Report, Niner Noise, 49ers Webzone, and is occasionally heard as a guest on San Francisco's 95.7 FM The Game and the Niners' flagship station, KNBR 680. Feel free to follow him, or direct any inquiries to his Twitter account.
All articles by Peter Panacy
More San Francisco 49ers News
-
49ers vs. Raiders in preseason: How to watch, stream, and listen, plus odds
The San Francisco 49ers travel to Allegiant Stadium to take on the Las Vegas Raiders in the final game of the 2026 preseason. This matchup marks the 44th preseason meeting between the two teams. San Francisco looks to improve to 23-20-1 in the preseason series against Las... -
49ers injury news: Kyle Shanahan provides 3 key updates after win over Raiders
San Francisco 49ers head coach Kyle Shanahan spoke to reporters after Thursday night's 18-12 preseason win over the Las Vegas Raiders at Allegiant Stadium, providing three key injury updates from the game. Rookie cornerback Ephesians Prysock, a fourth-round pick in the 2026... -
Recap: 49ers finish preseason with 18-12 win over Raiders in field goal fest
The final game of the preseason wasn't exactly a thriller, but they were at least able to close out with a win over the Las Vegas Raiders with the help of kicker Eddy Pineiro. In a battle of field goals, Pineiro out-dueled Raiders kicker Matt Gay, connecting on all six of... -
49ers insider reveals what to expect from Deebo Samuel in 2026
The potential impact of Deebo Samuel in the San Francisco 49ers' offense has somewhat flown under the radar as the start of the 2026 NFL season approaches. The truth is, Samuel has quietly put together a solid training camp. More importantly, unlike most of the other 49ers...