Wide receivers Dante Pettis and Kendrick Bourne will likely continue to see more playing time with Pierre Garçon being ruled out. Sunday will be Garçon's fourth-straight missed game and his fifth in six games as he continues to be burdened by a knee injury.
Pettis saw 71 snaps on offense against the Seattle Seahawks with both Garçon and Marquise Goodwin out of the lineup while Bourne saw 67. Goodwin is expected to play against Denver.
As expected, running back Matt Breida and safety Jaquiski Tartt have been ruled out. Head coach Kyle Shanahan told reporters on Friday that Jeff Wilson Jr. will start at running back in place of Breida.
Below are the official injury reports for the 49ers and Broncos. Also included are Friday's practice participation reports, which were provided by the 49ers Communications staff.
San Francisco 49ers
Out
RB Matt Breida (ankle), WR Pierre Garçon (knee), S Jaquiski Tartt (shoulder)
Questionable
CB K'Waun Williams (knee)
Denver Broncos
Out
LB Shaquil Barrett (hip), CB Tramaine Brock (ribs), CB Chris Harris (fibula)
Questionable
LB Brandon Marshall (knee)
San Francisco 49ers Friday Practice
Did Not Participate In Practice
RB Matt Breida (ankle), WR Pierre Garçon (knee), S Jaquiski Tartt (shoulder)
Limited Participation in Practice
CB K'Waun Williams (knee)
Full Participation in Practice
S Antone Exum (knee), G Joshua Garnett (thumb), LB Mark Nzeocha (thigh), S D.J. Reed (heel, chest), C Weston Richburg (knee), LB Malcolm Smith (Achilles), T Joe Staley (not injury related), G Laken Tomlinson (hip)
Denver Broncos Friday Practice
Did Not Participate In Practice
LB Shaquil Barrett (hip), CB Tramaine Brock (ribs), CB Chris Harris (fibula)
Limited Participation in Practice
LB Todd Davis (foot), DT Shelby Harris (hip), LB Brandon Marshall (knee)
Full Participation in Practice
LB Josey Jewell (ankle), WR Courtland Sutton (ankle), DE Derek Wolfe (ribs)
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