The San Francisco 49ers are coming off of a devastating loss at Arrowhead Stadium on Sunday — and that is not in reference to the final score. The 49ers lost quarterback Jimmy Garoppolo to a torn ACL late during the 38-27 loss to the Kansas City Chiefs. The team will move forward with second-year player C.J. Beathard as its starting signal caller.

The 49ers' Week 4 opponent, the Los Angeles Chargers, are coming off of a 35-23 loss to the Los Angeles Rams. Both teams are 1-2 heading into the matchup at the StubHub Center in Carson, California.


As things stand now, Vegas oddsmakers have the home-team Chargers listed as anywhere from 9.5- to 11.5-point favorites over Beathard and the visiting 49ers, according to various casinos and betting sites.

The spread consensus has the Chargers as 10.5-point favorites. Those numbers could change as the game draws near. The over/under for Sunday's game is listed at 47.5 points.

The then-San Diego Chargers came out on top in overtime by a score of 38-35 the last time the two teams met — a December 20, 2014 matchup at Levi's Stadium. The Chargers have won four straight against the 49ers dating back to 2002.

The 49ers and Chargers kick off at 1:25 p.m. PT on Sunday.

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