The Chiefs put up 38 points on the Los Angeles Chargers during Week 1 and on Sunday scored 42 against the Pittsburgh Steelers. Both games were on the road and Sunday will be Kansas City's home opener at Arrowhead Stadium.
The team tasked with stopping Mahomes and the red-hot Chiefs offense? The San Francisco 49ers.
Veteran cornerback Richard Sherman spoke with reporters on Thursday and was asked about the Chiefs' second-year quarterback.
"[Mahomes] trusts what he sees, he takes shots, he takes risks, he's efficient," Sherman said. "It's Andy Reid's offense. Even when Alex (Smith) was there, he does a great job scheming people up and getting people open. A lot of misdirection. You've got to be prepared for all of it."
What can Sherman and the 49ers defense do to stop Mahomes and the speedy offensive weapons around him? The cornerback has already reviewed the film of Pittsburgh's loss and feels there are lessons to be learned from it.
"You just see what the defense is doing," Sherman said. "Are they playing sound? Are they playing efficiently? Or are there a ton of busts?
"There were a lot of busts in the Pittsburgh game. A lot of guys out of position. It looked like they just tried to do too much. They had a bunch of checks. Any time you try to scheme up for every single play you're going to get, it's going to be tough. I think they made it way too complicated.
"You know, [Mahomes] made great plays and great throws but there were a lot of guys running scot-free, buck naked, wide open. You've got to play more sound than that."
The 49ers and Chiefs kick off from Arrowhead Stadium on Sunday at 10:00 a.m. PT (12:00 p.m. CT).
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