49ers' five biggest roster holes heading into 2018

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• 49ers place RB on season-ending IR and re-sign recently released RB
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• 49ers place running back on IR ahead of Chargers game, re-sign veteran
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• Chargers rookie on 49ers joint practice: 'We tore them up'
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• 49ers' Vita Vea trade hopes dashed after Buccaneers agree to $30 million extension
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• 49ers rookie to get another look at crucial position against Chargers
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• Has Kyle Shanahan assembled the best WR group of his 49ers tenure?
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