The Detroit Lions will be without 75 percent of their starting secondary, as cornerbacks Dwight Bentley and Chris Houston and free safety Louis Delmas are inactive for tonight's game against the San Francisco 49ers. With Bentley and Houston out, the Lions will start Jacob Lacey and Drayton Florence at the cornerback position. For the 49ers, running back Brandon Jacobs and wide receiver/return specialist Ted Ginn are inactive after being listed as "questionable" on this week's injury report. First round wide receiver A.J. Jenkins and second round running back LaMichael James are also inactive, which means Kendall Hunter will be the lone tailback active behind Frank Gore. Hunter (kicks) Kyle Williams (punts) will once again handle the return duties for the 49ers. Here's the full list of inactives for tonight's game: Detroit : QB Kellen Moore, OT Jason Fox, OT Corey Hilliard, LB Travis Lewis, CB Dwight Bentley, CB Chris Houston, S Louis Delmas San Francisco : RB Brandon Jacobs, RB LaMichael James, WR Ted Ginn, WR A.J. Jenkins, TE Garrett Celek, G Joe Looney, NT Ian Williams