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- September 25, 2022; 5:20 pm (PT)
- Line: 49ers -1.5.; o/u 44.5
- Venue: Empower Field at Mile High
Injury Report
49ers:
Out: OL Daniel Brunskill (hamstring), RB Tyrion Davis-Price (ankle), TE Tyler Kroft (knee)
Questionable: DL Arik Armstead (foot), T Colton McKivitz (ankle)
Broncos:
Out: CB Darius Phillips (hamstring)
Questionable: WR Jerry Jeudy (rib, shoulder), CB Patrick Surtain (shoulder), WR Tyrie Cleveland (hamstring), LB Jonathon Cooper (hamstring), WR K.J. Hamler (knee, hip), LB Josey Jewell (calf, knee), DE Dre'Mont Jones (neck), G Quinn Meinerz (hamstring), DT Mike Purcell (elbow), T Billy Turner (knee)