Al Sacco talks all things 49ers following preseason Week 1

Kyle Shanahan didn't sound too concerned about Jordan Reed's injury after the San Francisco 49ers' 36-9 victory over the New York Giants. He was optimistic that his tight end didn't suffer any long-term damage, noting that the 49ers would learn more tomorrow. Reed appeared to roll his ankle during the first quarter but returned in the second. The 49ers later ruled the tight end out after the television broadcast showed the team's medical staff examining Reed's left knee and leg. Shanahan said Reed indeed sustained ankle and knee injuries. Cornerback Emmanuel Moseley was ruled out with a concussion after a collision in the second quarter with safety Jaquiski Tartt as the two defenders attempted to tackle Giants quarterback Daniel

San Francisco 49ers head coach Kyle Shanahan spoke with reporters on Monday, the day after the team's 24-20 Week 1 loss to the Arizona Cardinals. Here is everything he had to say. Transcript provided by the San Francisco 49ers Communications staff. On WR Deebo Samuel, what happened last week that changed your thinking from him being close to him being on IR and did he have a setback? "Yeah, we didn't think it was a setback because he was just real sore after running one day, but the soreness never got better. It just got worse and worse after one specific day. Usually after one day when it was sore, we thought it was just because he worked it hard, but when that got worse each day and not better, we knew it ended up being a

Raheem Mostert joined KNBR on Wednesday morning for a lengthy interview on the Murph & Mac show. The San Francisco 49ers running back knows that losing on Sunday to the Arizona Cardinals was a disappointment, but he and his teammates aren't dwelling on it. "For me, personally, I think that game just kind of woke the beast up a little bit as far as where we want to go," Mostert said. "We've just got to take care of business this weekend, and handle what we can control, and go out there and try to get another win." San Francisco begins a two-game road trip to face the New York Jets and New York Giants in back-to-back games at MetLife Stadium. 49ers fans will see a familiar face on the opposing sideline, as 16-year veteran running back