The 49ers are coming off of a 43-18 loss against the Pittsburgh Steelers. The Cardinals are coming off of a 48-23 victory against the Chicago Bears.
Today's game will be the 49ers' first against an NFC West opponent. In 2014, each team won their home match-ups, but it's the 49ers that have won five of the last six meetings between the two teams.
Jim Tomsula has already beaten Arizona during his NFL head coaching career. In 2010, he guided the 49ers to a 38-7 victory in the team's final game of the season has the interim head coach.
QB Colin Kaepernick is looking to build on one of the few positives that the team had against the Steelers last week. He is coming off of his fourth career 300+ yard passing game. He was 33 of 46 for 335 yards, and two touchdowns for a passer rating of 106.7. He paired with WR Torrey Smith for a 75 yard touchdown, the longest of Smith's career. The offensive line, especially the right side, will have to give Kaepernick more time. The Steelers got to him five times last week and won the battle at the line of scrimmage for the majority of the game.
The 49ers defense will look to rebound from a game where they allowed QB Ben Roethlisberger to complete 21 of 27 for 369 yards, and three touchdowns for a passer rating of 155.8. He picked the defensive secondary, one of the team's offseason question marks, apart with the deep ball. They will be facing another tough task as they prepare to go up against Cardinals QB Carson Palmer, who has a passer rating of 124.4 this season.
For the second week in a row, RB Reggie Bush will not make the road trip with his teammates as he recovers from the calf strain that he suffered during week 1.
Kickoff: Sunday, September 27 at 1:05 PM PT
Television: The game will be televised on FOX (Check 506 Sports to see if it is local)
Bay Area Radio: KGO 810 & The Bone 107.7 (Other radio affiliates)
Spanish Radio: KTRB 860
Australian Radio: Triple M
Last Meeting: 12/28/14, 49ers win 20-17, at SF
All-Time Matchup: 49ers lead series 29-18
Betting: The Cardinals are 6.5 point favorites.
NFL Fan Picks: 73% pick the Cardinals to win according to Yahoo! Sports
49ers Fan Picks: Within our Pick 'em Contest, 53% believe the Cardinal will win
49ers Schedule: View full schedule
Cardinals News: Cardinals news at Problitz.com
Follow Game Online: NFL.com's Game Center
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Injury Report
| Team | Pos | Player | Injury | Status |
|---|---|---|---|---|
| 49ers | TE | Blake Bell | Back | Probable |
| 49ers | G | Alex Boone | Shoulder | Probable |
| 49ers | LB | NaVorro Bowman | Not injury related | Probable |
| 49ers | RB | Reggie Bush | Calf | Out |
| 49ers | WR | Bruce Ellington | Ankle | Questionable |
| 49ers | RB | Carlos Hyde | Quadriceps | Probable |
| 49ers | TE | Vance McDonald | Knee | Questionable |
| 49ers | WR | Torrey Smith | Knee | Probable |
| Cardinals | S | Deone Bucannon | Groin | Probable |
| Cardinals | RB | Andre Ellington | Knee | Doubtful |
| Cardinals | G | Mike Iupati | Knee | Questionable |
| Cardinals | S | Tony Jefferson | Hamstring | Probable |
| Cardinals | WR | J.J. Nelson | Shoulder | Out |
| Cardinals | LB | Alex Okafor | Shoulder | Probable |
| Cardinals | LB | LaMarr Woodley | Shoulder | Probable |
Game Averages (Rank)
| 49ers | Cardinals | |
|---|---|---|
|
19.0 (24th)
|
Offense Pts
|
39.5 (1st)
|
|
402.0 (4th)
|
Offense Yds
|
363.5 (11th)
|
|
231.5 (17th)
|
Offense Pass
|
246.0 (13th)
|
|
170.5 (1st)
|
Offense Rush
|
117.5 (13th)
|
|
23.0 (16th)
|
Defense Pts Allowed
|
21.0 (11th)
|
|
350.5 (16th)
|
Defense Yds Allowed
|
371.5 (22nd)
|
|
273.0 (26th)
|
Defense Pass Allowed
|
290.0 (28th)
|
|
77.5 (6th)
|
Defense Rush Allowed
|
81.5 (10th)
|
Game Articles
49ers could face a big problem in Cardinals' Calais Campbell
The Mercury News
49ers' offensive line will be sternly tested again
San Francisco Chronicle
Preview: 49ers vs. Cardinals
The Mercury News
Game Preview: Five Things to Watch When the 49ers Visit the Cardinals
49ers.com
49ers will keep it close vs. Arizona, but can they win?
Press Democrat
Sacramento Bee
After failed test, 49ers have chance to rebound in Arizona
San Francisco Chronicle
No Bruce Ellington, Vance McDonald today for 49ers
Sacramento Bee
