NFL Nation's Bill Williamson examines the three biggest issues facing the San Francisco 49ers heading into training camp.The holdouts: The 49ers, fresh off three straight trips to the NFC title game and seemingly poised for another long postseason run, have the weathered many storms this offseason.Yes, there are some issues that still linger. The 49ers do not know if tight end Vernon Davis and/or guard Alex Boone will continue their holdouts into training camp.