SANTA CLARA, Calif. – San Francisco 49ers coach Jim Harbaugh refused to say the team's offensive line, which until recently has been the model of durability, will be without two integral components Sunday in a pivotal game against visiting Seattle.When asked if star left tackle Joe Staley and standout left guard Mike Iupati could play, Harbaugh said "I wouldn't rule it out."However, both players did not practice. They were seen working hard on elliptical machines during the beginning stages of practices.