SANTA CLARA, Calif. -- One of the biggest problems for the San Francisco 49ers in the first quarter of the season has been its inability to get into a rhythm on offense.ESPN.com's Mike Sando came up with a telling statistic: The 49ers gave gone three-and-out on 43.1 percent of their offensive series. It's the fourth highest percentage in the league.Getting into an offensive rhythm was a big problem in San Francisco's two losses to Seattle and Indianapolis.