There are four San Francisco 49ers listed as questionable to play Sunday against Indianapolis, the biggest question mark being tight end Vernon Davis.Davis missed the entire week of practice with a hamstring injury he tweaked at Seattle. This was not unexpected; Davis tweeted this week that he would rest but be able to play. Coach Jim Harbaugh said Friday that Davis is a game-time decision.The other San Francisco players listed as questionable are defensive lineman Ray McDonald (two sprained ankles), safety Eric Reid (concussion) and running back LaMichael James (knee).