The 49ers will travel across the country to face the New England Patriots in a battle between division leaders on Sunday Night Football. San Francisco leads the all-time series 7-4 and this matchup marks the first primetime game between the two clubs.

Last week, San Francisco (9-3-1) defeated the Miami Dolphins, 27-13. The 49ers defense held the Dolphins to just 227 yards of offense as linebacker Aldon Smith recorded 2 sacks. With 19.5 sacks on the season, Smith set the single season franchise record, surpassing Hall of Fame defensive end Fred Dean (17.5 sacks in 1983).

The 49ers rushed for 155 yards and 3 touchdowns on 28 carries against Miami. Running back Frank Gore eclipsed the 1,000 yard plateau for the season, marking his franchise record 6th, 1,000 yard season. Quarterback Colin Kaepernick also added a 50 yard touchdown run, the longest touchdown run by a quarterback in franchise history.

The Patriots (10-3) are coming off of a 42-14 win over the Houston Texans.

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The game kicks off at 5:20 PM PT and, as usual, you can visit 49erswebzone.com for the latest news and updates during and after the game.

The game will be televised on NBC. The radio broadcast of the game will be on KGO 810 AM and The Bone 107.7 FM.

Within our 2012 NFL Pick 'Em Contest, 70% of fans fans believe that the 49ers will win this game.

Within Sportstacular, a popular mobile phone scores application, 60% of fans believe that the Patriots will win this game.

You can follow the game live on NFL.com's Game Center.

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