I don't want to jinx anything but I will say this:
Although I like Moreno and the Broncos have some decent RBs I think their offense is a shadow of what it use to be with Cutler. We all know run D is our strength and has been even when we where at the bottom of the league in pass D our Run D was always in the middle of the pack. I expect to see what Coffee and Sheets can do. I want to get Vernon Davis off to a good start this year. Denver's D plain stunk it up last year ranking 29th with 375 yards per game. Dawkins should help but Alphonso Smith (2nd round) was there first defensive player taken. He won't be an immediate impact in my opinion. So unless Nolan makes that big of presence their D should be about the same.
I say 20-13 49ers
Edit: P.S. I didn't look at any other posts before predicting. Looking back 13 for the Broncos seems to be a popular number. I'd expect low scoring games all season from us and our opponents.
[ Edited by Gore_21 on Aug 14, 2009 at 6:24 AM ]