San Francisco 49ers TE Garrett Celek went down after blocking during a running play in the first quarter of the team's game against the Arizona Cardinals. He was carted off of the field and is questionable to return with an ankle injury. Trainers kept his left leg immobile while carting him to the locker room.

TE Vance McDonald replaced Celek for the 49ers. Rookie Blake Bell is the only other tight end active for this game.