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Interim head coach Jim Tomsula led the San Francisco 49ers to a 38-7 rout over the visiting Arizona Cardinals in their final game of the 2010 season.
In what could be his last game in San Francisco, Alex Smith was 15 of 29 for 276 yards and two touchdowns.
Brian Westbrook carried the ball for 79 yards and two more touchdowns.
Next, the 49ers look to the offseason to hire a new G.M. and head coach. Stay here during the entire offseason as 49erswebzone.com covers the G.M. hiring, head coach search, free agency, the NFL Draft, and much more.
View gameday stats at NFL.com's Game Center.
You can also discuss the game with fans in the 49erswebzone.com forums.