The San Francisco 49ers lost to the Carolina Panthers by the score of 23-20 on Sunday. It was the Panthers' first win of the season and the 49ers drop to a record of 1-6.

Quarterback Alex Smith left the game with a sprained shoulder early in the 3rd quarter and was replaced by David Carr. Carr was 5 of 13 for 67 yards and an interception. Smith was 9 of 19 for 129 yards and a touchdown.

Next, the team will travel overseas to London to play the Denver Broncos.

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