Tonight, the San Francisco 49ers will play their first home game of the 2010 season against the defending world champion New Orleans Saints.

The game kicks off at 5:30 pm and as usual, you can visit 49erswebzone.com for the latest news and updates during and after the game.

Within our NFL Pick 'em Contest, 41% of fans believe that the 49ers will win this game.

Within Sportstacular, a popular mobile phone scores app, 20% of fans believe that the 49ers will win this game.

You can follow the game live on NFL.com's Game Center.

You can also discuss the game with fans in the 49erswebzone.com forums.